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Trends in Oncology

Radiopharmaceutical

Radiopharmaceutical Efficacy Studies in PDX Models: Why Tumor Diversity Matters

Radiopharmaceutical

Radiochemistry 101 for ADC Teams: A Practical Guide for Biodistribution Studies

Radiopharmaceutical

FDA Guidance: The Future of Radiopharmaceutical Development

Radiopharmaceutical

Radiopharmaceuticals in Cancer Treatment: Insights from Mike Ritchie

Radiopharmaceutical

Seeing Beyond Efficacy: How Radiolabeling Advances ADC Drug Development

Radiopharmaceutical

How Radioisotopes Are Being Used to De-Risk Antibody-Drug Conjugate (ADC) Development

Radiopharmaceutical

Why PDX Models Are Essential for Radiopharmaceutical Testing

A DNA helices showing the power of data in oncology drug discovery.

LUMIN

Beyond TCGA: TumorGraft’s New Frontier in Cancer Research

IHC

Predicting ADC Efficacy Using IHC and NGS

Bispecific antibody binding target protein on the tumor cell surface.

Immuno-Oncology

Advancements in bispecific antibody research and innovative platforms

Multiple Myeloma cells in the blood stream together with red blood cells.

Hematological Malignancies

Advances in BCMA-Targeting Therapies: Takeaways from ASH2024

A T-cell is attacking and killing a cancer cell.

3d co cultures

How to Develop Relevant Co-Culture Models of the Tumor Microenvironment

Blood cancer cells in the blood stream.

Hematologic Malignancies

Bad Blood: Modeling Biologically Relevant Blood Cancer Studies

Primary blood cancer cells surrounded by red blood cells in the blood flow.

Hematologic Malignancies

Primary Blood Cancer Models: Getting Blood from a Stone

Acute Myeloid Leukemia Cells in the blood stream.

Acute Myeloid Leukemia

It’s All in the Blood: Choosing Clinically Relevant Blood Cancer Models for Research

Heterogenous tumor cells in PDX models showing different characteristics.

PDX Models

PDX Models: Masters of Diversity

Immune cells attacking 3D tumor model cells.

Immuno-Oncology

A Step-by-Step Guide to Design a 3D Tumor Model Co-Culture Study

Use multi-omics and multi modal metadata combined to clinical annotations to elevate your model selection.

PDX Models

How to use metadata as your model selection GPS

Immune cells attacking a tumor cell during an immuno-oncology in vivo study.

Immuno-Oncology

5 Essential Steps for a Successful Immuno-Oncology In Vivo Study

Preclinical CLL models derived from patients aid in the development of novel therapies.

Hematological Malignancies

Development of Innovative Therapies Utilizing Preclinical CLL Models

Champions' TumorGraft3D - 3D organoid models for ex vivo drug testing.

Solid Tumor Oncology

Using 3D Ex Vivo Tumor Models for Oncology Research: An Expert Guide

Blog : Navigating Clinical Specialty Testing: Key Insights into Regulatory Compliance

Clinical Specialty Testing

Navigating Clinical Specialty Testing: Key Insights into Regulatory Compliance

Accelerating innovative cancer drug development with pre-treated PDX tumor models. Champions Oncology Blog April 18 2024

Solid Tumor Oncology

Accelerating Innovation & Drug Development with Pre-treated PDX Models

A DNA helic being decoded with next generation sequencing techniques.

LUMIN

Deciphering CNV: Utilizing Gene Copy Number Variation Data in Lumin

Triple-Negative Breast Cancer (TNBC) cells interacting in the tumor microenvironment.

immunooncology

The Evolution of Treatment in TNBC: A Closer Look at Pembrolizumab

Renal cell carcinoma cells proliferating in the tumor microenvironment.

Solid Tumor Oncology

Immune Checkpoint Blockade Strategies in Renal Cell Carcinoma

Immune system lymphocyte recognizing, attacking, and killing a cancer cell.

Syngeneic Models

Choosing the RIGHT Model - Syngeneic versus Humanized Mouse Models

Mantle cell lymphoma (MCL) cells floating in a blood vessel after proliferating in the secondary follicle of the lymph node

BTK inhibitors

Advancing the Battle Against Mantle Cell Lymphoma

Double strand DNA helix in a cloud of computational connection representing the RNA-seq bioinformatic data analysis.

NGS

Exploring DRUG-seq: Revolutionizing RNA-seq in Oncology Research

Preclinical Flow Cytometry

Developing Flow Cytometry Assays in Non-Human Primates (NHPs)

Microscopic view of acute myeloid leukemia (AML) cells surrounded by blood cells in a blood vessel

Hematological Malignancies

Triplet Therapy for IDH1-Mutant AML Tumors

Cholangiocarcinoma cell in the biliary duct in the liver showing characteristics of aggressive tumor.

Solid Tumor Oncology

Providing Optimal Clinical Care for Cholangiocarcinoma Subtypes

AML cells phenotyped by Flow Cytometry

Hematological Malignancies

A Needle in a Haystack: Finding Rare AML Populations by Flow Cytometry

Tumor cell attacked by CAR T cells engineered to recognize specific surface antigens on the tumor cell membrane.

Immuno-Oncology

Enhancing CAR T Cell Therapy: Optimizing Preparation for Superior Results

Microscopic view of Multiple Myeloma (MM) cells surrounding healthy red blood cells (RBCs) that are circulating in a blood vessel.

Hematological Malignancies

Unlocking the Potential of CAR-T Therapy for Treatment of Multiple Myeloma

A group of colorectal cancer cells in their environment showing malignant features.

Solid Tumor Oncology

Benefits of Immuno-Oncology for Colorectal Cancer

Plasmacytoid carcinoma of the urinary bladder

IHC

Immunohistochemistry: a Powerful Tool in Cancer Research

Automated fluid handling machine dispensing reagents in a 96-well plate for ex vivo culture assays.

Organoids

Uncovering Advantages and Disadvantages of Ex Vivo Culture in Preclinical Cancer Research

Harnessing the Power of Oncolytic Viruses in the Fight Against Cancer a Champions Blog

Solid Tumor Oncology

Harnessing the Power of Oncolytic Viruses in the Fight Against Cancer

Cancer cell invading the surrounding tissue in a tumor PDX mouse model.

Solid Tumor Oncology

Ultimate Guide: Designing a Mouse Clinical Trial & Data Analysis

Microscopic view of Myelodysplastic Syndrome (MDS) cells with varied shapes surrounding healthy red blood cells (RBCs) that are circulating in a blood vessel.

Hematological Malignancies

Advancing Therapeutic Strategies for Myelodysplastic Syndrome

Pancreatic cancer cells floating in culture media.

Solid Tumor Oncology

A Multi-Omics Driven Approach for Advancements in Pancreatic Cancer

3D rendition of a protein kinase showing each protein domain in a different color.

Proteomics

4D Proteomics: Adding Dimension to Protein Detection

Non-small cell lung cancer (NSCLC) cells aggregating and forming cell to cell connections necessary for proliferation and cell functions.

Solid Tumor Oncology

Recent Developments in Targeted Therapy for Non-Small Cell Lung Cancer

Chronic Lymphocytic Leukemia B cells in the blood stream surrounded by numerous red blood cells.

Hematological Malignancies

Potentials of BTK Therapies for Chronic Lymphocytic Leukemia

The Complex Case of Hepatocellular Carcinoma Clinical Management

Solid Tumor Oncology

The Complex Case of Hepatocellular Carcinoma Clinical Management

Hitting the Target: Latest Developments in Anti-Her2 Therapy

Solid Tumor Oncology

Hitting the Target: Latest Developments in Anti-Her2 Therapy

New Blog: Prostate Cancer - Drivers of Genetic Mutations & their Role in Disease progression

Solid Tumor Oncology

Prostate Cancer - Drivers of Genetic Mutations & Their Role in Disease Progression

Translational Oncology

The Benefits of Cell Line-Derived Xenograft Models for Preclinical Oncology Screening

Solid Tumor Oncology

ERK at Work - Targeting the ERK Pathway in Cancer

Champions' Specialty Testing Services: PBMC Isolation

Flow Cytometry

Unveiling the Secrets of PBMC Isolation Tubes: Clinching Clinical Trial Success with the Right Tools

3-D rendering of human cancer cells

Solid Tumor Oncology

Sarcoma Immunotherapeutic Strategies

3D rendering of cancer cells

Solid Tumor Oncology

PARP Inhibitors for Ovarian Cancer Treatment

Next Generation Sequencing

RNAseq and Whole Transcriptome Sequencing: Understanding Gene Expression Analysis

CRISPR/Cas9-Based Immunotherapy for Gastrointestinal Cancer

Solid Tumor Oncology

Current Trends in Gastrointestinal Cancer – CRISPR/Cas9-based Immunotherapy

Receptor Occupancy and Flow Cytometry

Clinical Flow Cytometry

Receptor Occupancy & Flow Cytometry

CD19-targeted therapies_blog_header

Hematological Malignancies

Understanding Relapse & Acquired Resistance to CD19-targeted Therapies

doctor holding electronic tablet looking at genomic, molecular data

NGS

Next-Generation Sequencing Applications for Preclinical Oncology Research

Ex Vivo Systems

Ex Vivo Platforms

Are you in the Matrix? Using Matrix vs Matrix-free assays in ex vivo culture platforms

Ex Vivo Hematologic Oncology Models improve therapeutic agent screening.

Ex Vivo Platforms

Top 3 Considerations for Using Ex Vivo Hematologic Models

Clinical Flow Cytometry scientist in the lab

Clinical Flow Cytometry

The Dos & Don’ts of Flow Cytometry in the Clinic

T Lymphocytes and Cancer Cell

Solid Tumor Oncology

Insights in Invasive Bladder Cancer

Solid Tumor Oncology

Head & Neck Cancers - New Mutation Insights Lead to New Therapies

Novel RNAs Insights Toward AML Development

Hematological Malignancies

Novel RNAs Insights Toward AML Development

Overcoming Drug Resistance in AML

Hematological Malignancies

Overcoming Drug Resistance in AML: Targeting Tricky Signaling Pathways

3D Rendering of a Natural Killer Cell (NK Cell) destroying a cancer cell

Immuno-Oncology

UnTIL We Meet Again: Testing TIL Therapies in an Ex Vivo Platform

Clinical Flow Cytometry

Clinical Flow Cytometry – Understanding GCLP Standards and Compliance

Solid Tumor Oncology

Targeted Therapy for Biliary Cancers

Leveraging IHC as a powerful clinical tool for IO therapies

IHC

Leveraging IHC as a powerful clinical tool for IO therapies

Representative image of DNA damage.

Solid Tumor Oncology

Evaluating DNA Damage in Preclinical PDX Models

Western Blot

Blotting Basics - Western Blot Applications in Preclinical Oncology Research

Flow cytometry as an in vivo model endpoint

Preclinical Flow Cytometry

Using Flow Cytometry as an In Vivo Study Endpoint

gene sequencing character string

NGS

Factors to Consider When Selecting Next-Generation Sequencing (NGS) Technology

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