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Interpreting HER2 Status: Intra- & Intertumoral Heterogeneity

Dec 2, 2022 2:27:00 PM / by Champions Oncology posted in IHC

The human epidermal growth factor receptor-2 (HER2) is a membrane protein with intracellular tyrosine kinase activity that regulates cell growth, proliferation, adhesion, and migration. HER2 overexpression is not only found in breast cancer, but also appears in other cancer types, including gastric, ovarian, uterine serous endometrial carcinoma, uterine cervix, colon, bladder, esophageal, head and neck, and lung cancers[1].

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