Ask the Expert: Amy Wesa, PhD, Director of Immuno-Oncology Research at Champions Oncology

Jun 4, 2020 3:40:32 PM / by Champions Oncology posted in immunohistochemistry

Amy Wesa, PhD, answers key questions about immuno-oncology and the current ex vivo platforms that are available at Champions Oncology, and were discussed in detail in her recent webinar.

 

  1. Does Champions have the ability to test immuno-oncology agents in these platforms?

Champions has extensive experience in humanized mouse models in solid tumor PDX and has a group of scientists with deep immuno-oncology know-how. We are actively developing platforms for evaluating IO agents in the context hematologic malignancy models and welcome the opportunity to develop custom assays as well.

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Ask an Expert: Dr. Tamara Laskowski, Senior Research Scientist from MD Anderson Cancer Center

May 11, 2020 12:48:51 PM / by Champions Oncology

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Ask an Expert: Dr. Tamara Laskowski, Senior Research Scientist from MD Anderson Cancer Center, answers key questions from her recent webinar.

  1. How long does it take to understand an assay from design to good reproductible data?
    It will depend on a few factors such as 1) The level of training of the person who is developing the assay, 2) The complexity of the assay they are developing, and 3) The support they have (e.g. mentors, peers who have advanced knowledge, ease of access to cytometer).

    If the user has some experience with flow cytometry and panel design, and has a good level of support, for a 5-7 color assay, in 2-3 weeks you should be able to have a panel designed, antibodies ordered, titrations performed, controls selected, single-color and biological controls empirically tested.
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